Monosomy 17 in potentially curable HER2-amplified breast cancer: prognostic and predictive impact

PURPOSE: HER2 copy number by fluorescence in situ hybridization (FISH) is typically reported relative to the centromere enumeration probe 17 (CEP17). HER2/CEP17 ratio could be impacted by alterations in the number of chromosome 17 copies. Monosomy of chromosome 17 (m17) is found in ~1,900 cases of e...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Page, David B., Wen, Hannah, Brogi, Edi, Dure, Dana, Ross, Dara, Spinelli, Kateri J., Patil, Sujata, Norton, Larry, Hudis, Clifford, McArthur, Heather L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405897/
https://ncbi.nlm.nih.gov/pubmed/28986743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4520-1
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