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Suppression of autophagy by BCR/ABL

Imatinib and second generation BCR/ABL tyrosine kinase inhibitors (TKIs) serve now as standard therapies for patients with chronic myelogenous leukemia (CML); however, CML stem cells are intrinsically insensitive to the cell death-inducing effects of TKIs, allowing the persistence of a “reservoir” o...

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Detalles Bibliográficos
Publicado en:Front Biosci (Schol Ed)
Autores principales: Calabretta, Bruno, Salomoni, Paolo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405106/
https://ncbi.nlm.nih.gov/pubmed/22202070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2741/278
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