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Tau and Alpha Synuclein Synergistic Effect in Neurodegenerative Diseases: When the Periphery Is the Core

In neuronal cells, tau is a microtubule-associated protein placed in axons and alpha synuclein is enriched at presynaptic terminals. They display a propensity to form pathologic aggregates, which are considered the underlying cause of Alzheimer’s and Parkinson’s diseases. Their functional impairment...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Vacchi, Elena, Kaelin-Lang, Alain, Melli, Giorgia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404325/
https://ncbi.nlm.nih.gov/pubmed/32708732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145030
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