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Fibrocystin Is Essential to Cellular Control of Adhesion and Epithelial Morphogenesis
Mutations of the Pkhd1 gene cause autosomal recessive polycystic kidney disease (ARPKD). Pkhd1 encodes fibrocystin/polyductin (FPC), a ciliary type I membrane protein of largely unknown function, suggested to affect adhesion signaling of cells. Contributions of epithelial cell adhesion and contracti...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7404311/ https://ncbi.nlm.nih.gov/pubmed/32698519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145140 |
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