LY75 Suppression in Mesenchymal Epithelial Ovarian Cancer Cells Generates a Stable Hybrid EOC Cellular Phenotype, Associated with Enhanced Tumor Initiation, Spreading and Resistance to Treatment in Orthotopic Xenograft Mouse Model

The implications of the epithelial–mesenchymal transition (EMT) mechanisms in the initiation and progression of epithelial ovarian cancer (EOC) remain poorly understood. We have previously shown that suppression of the antigen receptor LY75 directs mesenchymal–epithelial transition (MET) in EOC cell...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Mehdi, Sadia, Macdonald, Elizabeth, Galpin, Kristianne, Landry, David A., Rodriguez, Galaxia, Vanderhyden, Barbara, Bachvarov, Dimcho
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404269/
https://ncbi.nlm.nih.gov/pubmed/32679765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21144992
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