Integrated Analysis of Tissue-Specific Promoter Methylation and Gene Expression Profile in Complex Diseases

This study investigated whether the promoter region of DNA methylation positively or negatively regulates tissue-specific genes (TSGs) and if it correlates with disease pathophysiology. We assessed tissue specificity metrics in five human tissues, using sequencing-based approaches, including 52 whol...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Lee, Kibaick, Moon, Sanghoon, Park, Mi-Jin, Koh, In-Uk, Choi, Nak-Hyeon, Yu, Ho-Yeong, Kim, Young Jin, Kong, Jinhwa, Kang, Hee Gyung, Kim, Song Cheol, Kim, Bong-Jo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404266/
https://ncbi.nlm.nih.gov/pubmed/32709145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145056
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