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Differential regulation of JAK/STAT-signaling in patients with ulcerative colitis and Crohn’s disease

In 2018, the pan-Janus kinase (JAK) inhibitor tofacitinib was launched for the treatment of ulcerative colitis (UC). Although tofacitinib has proven efficacious in patients with active UC, it failed in patients with Crohn’s disease (CD). This finding strongly hints at a different contribution of JAK...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:World J Gastroenterol
Egile Nagusiak: Cordes, Friederike, Foell, Dirk, Ding, John Nik, Varga, Georg, Bettenworth, Dominik
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Baishideng Publishing Group Inc 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403801/
https://ncbi.nlm.nih.gov/pubmed/32821070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v26.i28.4055
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