Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx)

BACKGROUND: In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and Gram-negative bacteria. TGC is metabolized and eliminated predominantly by the liver. Critical illness-induced liver failure may have a profo...

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Bibliografiske detaljer
Udgivet i:Ann Intensive Care
Main Authors: Alraish, Rawan, Wicha, Sebastian G., Frey, Otto R., Roehr, Anka C., Pratschke, Johann, Stockmann, Martin, Wuensch, Tilo, Kaffarnik, Magnus
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403243/
https://ncbi.nlm.nih.gov/pubmed/32754775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-020-00707-2
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