Immunomodulatory Properties of Leishmania Extracellular Vesicles During Host-Parasite Interaction: Differential Activation of TLRs and NF-κB Translocation by Dermotropic and Viscerotropic Species

Leishmania infection causes considerable human morbidity and may develop into a deadly visceral form in endemic regions. The parasite infects macrophages where they can replicate intracellularly. Furthermore, they modulate host immune responses by using virulence factors (lipophosphoglycan, glycopro...

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Udgivet i:Front Cell Infect Microbiol
Main Authors: Nogueira, Paula Monalisa, de Menezes-Neto, Armando, Borges, Valéria M., Descoteaux, Albert, Torrecilhas, Ana Claudia, Xander, Patrícia, Revach, Or-Yam, Regev-Rudzki, Neta, Soares, Rodrigo Pedro
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cellular and Infection Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403210/
https://ncbi.nlm.nih.gov/pubmed/32850481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00380
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