Both Methylation and Copy Number Variation Participated in the Varied Expression of PRAME in Multiple Myeloma

PURPOSE: The cancer-testis antigen, which is a preferentially expressed antigen of melanoma (PRAME), is an ideal target for immunotherapy and cancer vaccines. Since the expression of this antigen is relevant to therapy responses, the heterogeneity in its expression and the underlying mechanism need...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Yang, Lu, Dao, Feng-Ting, Chang, Yan, Wang, Ya-Zhe, Li, Ling-Di, Chen, Wen-Min, Long, Ling-Yu, Liu, Yan-Rong, Lu, Jin, Liu, Kai-Yan, Qin, Ya-Zhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402861/
https://ncbi.nlm.nih.gov/pubmed/32801773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S240979
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