Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

Excitation-inhibition (E:I) imbalance is theorized as an important pathophysiological mechanism in autism. Autism affects males more frequently than females and sex-related mechanisms (e.g., X-linked genes, androgen hormones) can influence E:I balance. This suggests that E:I imbalance may affect aut...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Trakoshis, Stavros, Martínez-Cañada, Pablo, Rocchi, Federico, Canella, Carola, You, Wonsang, Chakrabarti, Bhismadev, Ruigrok, Amber NV, Bullmore, Edward T, Suckling, John, Markicevic, Marija, Zerbi, Valerio, Baron-Cohen, Simon, Gozzi, Alessandro, Lai, Meng-Chuan, Panzeri, Stefano, Lombardo, Michael V
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402681/
https://ncbi.nlm.nih.gov/pubmed/32746967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55684
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