Microglial calcium signaling is attuned to neuronal activity in awake mice

Microglial calcium signaling underlies a number of key physiological and pathological processes in situ, but has not been studied in vivo in awake mice. Using multiple GCaMP6 variants targeted to microglia, we assessed how microglial calcium signaling responds to alterations in neuronal activity acr...

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Bibliographic Details
Published in:eLife
Main Authors: Umpierre, Anthony D, Bystrom, Lauren L, Ying, Yanlu, Liu, Yong U, Worrell, Gregory, Wu, Long-Jun
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402678/
https://ncbi.nlm.nih.gov/pubmed/32716294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56502
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