Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

Coronavirus disease 2019 (COVID-19) is characterized by distinct patterns of disease progression that suggest diverse host immune responses. We performed an integrated immune analysis on a cohort of 50 COVID-19 patients with various disease severity. A distinct phenotype was observed in severe and c...

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Publicado en:Science
Main Authors: Hadjadj, Jérôme, Yatim, Nader, Barnabei, Laura, Corneau, Aurélien, Boussier, Jeremy, Smith, Nikaïa, Péré, Hélène, Charbit, Bruno, Bondet, Vincent, Chenevier-Gobeaux, Camille, Breillat, Paul, Carlier, Nicolas, Gauzit, Rémy, Morbieu, Caroline, Pène, Frédéric, Marin, Nathalie, Roche, Nicolas, Szwebel, Tali-Anne, Merkling, Sarah H., Treluyer, Jean-Marc, Veyer, David, Mouthon, Luc, Blanc, Catherine, Tharaux, Pierre-Louis, Rozenberg, Flore, Fischer, Alain, Duffy, Darragh, Rieux-Laucat, Frédéric, Kernéis, Solen, Terrier, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
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Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402632/
https://ncbi.nlm.nih.gov/pubmed/32661059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc6027
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