Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody

The COVID-19 pandemic caused by the SARS-CoV-2 virus has resulted in an unprecedented public health crisis. There are no approved vaccines or therapeutics for treating COVID-19. Here we reported a humanized monoclonal antibody, H014, efficiently neutralizes SARS-CoV-2 and SARS-CoV pseudoviruses as w...

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Udgivet i:Science
Main Authors: Lv, Zhe, Deng, Yong-Qiang, Ye, Qing, Cao, Lei, Sun, Chun-Yun, Fan, Changfa, Huang, Weijin, Sun, Shihui, Sun, Yao, Zhu, Ling, Chen, Qi, Wang, Nan, Nie, Jianhui, Cui, Zhen, Zhu, Dandan, Shaw, Neil, Li, Xiao-Feng, Li, Qianqian, Xie, Liangzhi, Wang, Youchun, Rao, Zihe, Qin, Cheng-Feng, Wang, Xiangxi
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402622/
https://ncbi.nlm.nih.gov/pubmed/32703908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc5881
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