Calmangafodipir Reduces Sensory Alterations and Prevents Intraepidermal Nerve Fibers Loss in a Mouse Model of Oxaliplatin Induced Peripheral Neurotoxicity

Oxaliplatin (OHP) is an antineoplastic compound able to induce peripheral neurotoxicity. Oxidative stress has been suggested to be a key factor in the development of OHP-related peripheral neurotoxicity. Mangafodipir, a contrast agent possessing mitochondrial superoxide dismutase (MnSOD)-mimetic act...

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Veröffentlicht in:Antioxidants (Basel)
Hauptverfasser: Canta, Annalisa, Chiorazzi, Alessia, Pozzi, Eleonora, Fumagalli, Giulia, Monza, Laura, Meregalli, Cristina, Carozzi, Valentina A., Rodriguez-Menendez, Virginia, Oggioni, Norberto, Näsström, Jacques, Marmiroli, Paola, Cavaletti, Guido
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402145/
https://ncbi.nlm.nih.gov/pubmed/32645985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9070594
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