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Endothelial Yes-Associated Protein 1 Promotes Astrocyte Proliferation and Maturation via Cytoplasmic Leukemia Inhibitory Factor Secretion in Oxygen-Induced Retinopathy

PURPOSE: Purpose The role of endothelial Yes-associated protein 1 (YAP) in the pathogenesis of retinal angiogenesis and the astrocyte network in the mouse oxygen-induced retinopathy (OIR) model is unknown. METHODS: For in vivo studies, OIR was induced in conditional endothelial YAP knockout mice and...

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Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Ai, Li-Qian-Yu, Zhu, Jing-Yi, Chen, Xi, Li, Xue, Luo, Lin-Lin, Hu, Qiu-Mei, Lin, Sen, Ye, Jian
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401846/
https://ncbi.nlm.nih.gov/pubmed/32271890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.4.1
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