CDK4/6 regulate lysosome biogenesis through TFEB/TFE3

Lysosomes are degradation and signaling organelles that adapt their biogenesis to meet many different cellular demands; however, it is unknown how lysosomes change their numbers for cell division. Here, we report that the cyclin-dependent kinases CDK4/6 regulate lysosome biogenesis during the cell c...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Yin, Qiuyuan, Jian, Youli, Xu, Meng, Huang, Xiahe, Wang, Niya, Liu, Zhifang, Li, Qian, Li, Jinglin, Zhou, Hejiang, Xu, Lin, Wang, Yingchun, Yang, Chonglin
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401801/
https://ncbi.nlm.nih.gov/pubmed/32662822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201911036
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