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Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice

Families with sequence similarity 170 members A and B (FAM170A and FAM170B) are testis-specific, paralogous proteins that share 31% amino acid identity and are conserved throughout mammals. While previous in vitro experiments suggested that FAM170B, an acrosome-localized protein, plays a role in the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biol Reprod
Prif Awduron: Devlin, Darius J, Nozawa, Kaori, Ikawa, Masahito, Matzuk, Martin M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401401/
https://ncbi.nlm.nih.gov/pubmed/32588889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioaa082
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