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Pterostilbene reduces endothelial cell apoptosis by regulation of the Nrf2-mediated TLR-4/MyD88/NF-κB pathway in a rat model of atherosclerosis

Endothelial cell injury in vascular arterial walls plays a crucial role in the pathological process of atherosclerosis. Pterostilbene, a stilbenoid chemically related to resveratrol, has anti-inflammatory, anti-apoptosis and antioxidant properties. However, the underlying mechanisms mediated by pter...

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Bibliografski detalji
Izdano u:Exp Ther Med
Glavni autori: Xiong, Xiaowei, Lu, Weihang, Zhang, Kaihua, Zhou, Weimin
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401285/
https://ncbi.nlm.nih.gov/pubmed/32782521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8923
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