Individual participant data meta‐analysis to examine interactions between treatment effect and participant‐level covariates: Statistical recommendations for conduct and planning

Precision medicine research often searches for treatment‐covariate interactions, which refers to when a treatment effect (eg, measured as a mean difference, odds ratio, hazard ratio) changes across values of a participant‐level covariate (eg, age, gender, biomarker). Single trials do not usually hav...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Stat Med
Hauptverfasser: Riley, Richard D., Debray, Thomas P.A., Fisher, David, Hattle, Miriam, Marlin, Nadine, Hoogland, Jeroen, Gueyffier, Francois, Staessen, Jan A., Wang, Jiguang, Moons, Karel G.M., Reitsma, Johannes B., Ensor, Joie
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2020
Schlagworte:
Tutorial in Biostatistics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401032/
https://ncbi.nlm.nih.gov/pubmed/32350891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8516
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