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Downregulation of the let-7 family of microRNAs may promote insulin receptor/insulin-like growth factor signalling pathways in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer type characterized by dysregulated cell signalling pathways and resistance to treatment. The insulin-like growth factor (IGF) signalling pathway has been identified to have a role in tumour progression and therapy resistance. However, i...

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Pubblicato in:Oncol Lett
Autori principali: Nweke, Ekene Emmanuel, Brand, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400736/
https://ncbi.nlm.nih.gov/pubmed/32782579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.11854
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