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PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins
PSGL-1 has recently been identified as an HIV restriction factor that inhibits HIV DNA synthesis and more potently, virion infectivity. But the underlying mechanisms of these inhibitions are unknown. Here we show that PSGL-1 directly binds to cellular actin filaments (F-actin) to restrict actin dyna...
Kaydedildi:
| Yayımlandı: | Cell Discov |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer Singapore
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7400672/ https://ncbi.nlm.nih.gov/pubmed/32802403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-0184-9 |
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