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Why Formalin-fixed, Paraffin-embedded Biospecimens Must Be Used in Genomic Medicine: An Evidence-based Review and Conclusion

Fresh-frozen tissue is the “gold standard” biospecimen type for next-generation sequencing (NGS). However, collecting frozen tissue is usually not feasible because clinical workflows deliver formalin-fixed, paraffin-embedded (FFPE) tissue blocks. Some clinicians and researchers are reticent to embra...

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Bibliographische Detailangaben
Veröffentlicht in:J Histochem Cytochem
Hauptverfasser: Mathieson, William, Thomas, Geraldine A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400666/
https://ncbi.nlm.nih.gov/pubmed/32697619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155420945050
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