Progesterone Attenuates Allodynia of Inflamed Temporomandibular Joint through Modulating Voltage-Gated Sodium Channel 1.7 in Trigeminal Ganglion

BACKGROUND: Women with temporomandibular disorders (TMDs) experience some amelioration of pain during pregnancy. Progesterone increases dramatically and steadily during pregnancy. Sodium channel 1.7 (Nav1.7) plays a prominent role in pain perceptions, as evidenced by deletion of Nav1.7 alone leading...

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Publicado en:Pain Res Manag
Autores principales: Bi, Rui-Yun, Zhang, Xiao-Yu, Zhang, Peng, Ding, Yun, Gan, Ye-Hua
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399782/
https://ncbi.nlm.nih.gov/pubmed/32774568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6582586
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