Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain

BACKGROUND: Microglia, the brain's principal immune cell, are increasingly implicated in Alzheimer's disease (AD), but the molecular interfaces through which these cells contribute to amyloid beta (Aβ)-related neurodegeneration are unclear. We recently identified microglial contributions t...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Crapser, Joshua D., Spangenberg, Elizabeth E., Barahona, Rocio A., Arreola, Miguel A., Hohsfield, Lindsay A., Green, Kim N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399129/
https://ncbi.nlm.nih.gov/pubmed/32745992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102919
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