Enhancement of Antitumor Efficacy of Paclitaxel-Loaded PEGylated Liposomes by N,N-Dimethyl Tertiary Amino Moiety in Pancreatic Cancer

INTRODUCTION: Pancreatic cancer, or pancreatic duct adenocarcinoma (PDAC), remains one of the most lethal cancers and features insidious onset, highly aggressive behavior and early distant metastasis. The dense fibrotic stroma surrounding tumor cells is thought to be a shield to resist the permeatio...

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Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Chen, Yang, Wang, Li, Luo, Shi, Hu, Jun, Huang, Xing, Li, Pei-Wen, Zhang, Yi, Wu, Chao, Tian, Bo-Le
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398872/
https://ncbi.nlm.nih.gov/pubmed/32801636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S261017
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