PRP4 Kinase Domain Loss Nullifies Drug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells

We have investigated the involvement of the pre-mRNA processing factor 4B (PRP4) kinase domain in mediating drug resistance. HCT116 cells were treated with curcumin, and apoptosis was assessed based on flow cytometry and the generation of reactive oxygen species (ROS). Cells were then transfected wi...

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Gepubliceerd in:Mol Cells
Hoofdauteurs: Ahmed, Muhammad Bilal, Islam, Salman Ul, Sonn, Jong Kyung, Lee, Young Sup
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Korean Society for Molecular and Cellular Biology 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398799/
https://ncbi.nlm.nih.gov/pubmed/32576716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2020.2263
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