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Activation of p53-dependent responses in tumour cells treated with a PARC-interacting peptide

We tested the activity of a p53 carboxy-terminal peptide containing the PARC-interacting region in cancer cells with wild type cytoplasmic p53. Peptide delivery was achieved by fusing it to the TAT transduction domain (TAT-p53-C-ter peptide). In a two-hybrid assay, the tetramerization domain (TD) of...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Vitali, Roberta, Cesi, Vincenzo, Tanno, Barbara, Ferrari-Amorotti, Giovanna, Dominici, Carlo, Calabretta, Bruno, Raschellà, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398582/
https://ncbi.nlm.nih.gov/pubmed/18230339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.01.093
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