Developmental loss of neurofibromin across distributed neuronal circuits drives excessive grooming in Drosophila

Neurofibromatosis type 1 is a monogenetic disorder that predisposes individuals to tumor formation and cognitive and behavioral symptoms. The neuronal circuitry and developmental events underlying these neurological symptoms are unknown. To better understand how mutations of the underlying gene (NF1...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: King, Lanikea B., Boto, Tamara, Botero, Valentina, Aviles, Ari M., Jomsky, Breanna M., Joseph, Chevara, Walker, James A., Tomchik, Seth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398555/
https://ncbi.nlm.nih.gov/pubmed/32697780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008920
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