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CD154 inhibits death of T cells via a Cis interaction with the α5β1 integrin

CD154 plays a major role in the pathogenesis of several autoimmune and inflammatory diseases. In addition to CD40, soluble CD154 (sCD154) binds to other receptors namely αIIbβ3, αMβ2, α5β1 and αvβ3 integrins. We have previously reported that binding of sCD154 to α5β1 integrin expressed on several hu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bachsais, Meriem, Salti, Suzanne, Zaoui, Kossay, Hassan, Ghada S., Aoudjit, Fawzi, Mourad, Walid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398495/
https://ncbi.nlm.nih.gov/pubmed/32745080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235753
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