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Structural Properties and Catalytic Implications of the SPASM Domain Iron-Sulfur Clusters in Methylorubrum extorquens PqqE

Understanding the relationship between the metallocofactor and its protein environment is the key to uncovering the mechanism of metalloenzymes. PqqE, a radical S-adenosylmethionine (RS) enzyme in pyrroloquinoline quinone biosynthesis, contains three iron-sulfur cluster binding sites. Two auxiliary...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Zhu, Wen, Walker, Lindsey M., Tao, Lizhi, Iavarone, Anthony T., Wei, Xuetong, Britt, R. David, Elliott, Sean J., Klinman, Judith P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398046/
https://ncbi.nlm.nih.gov/pubmed/32643933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c02044
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