A limited set of transcriptional programs define major cell types

We have produced RNA sequencing data for 53 primary cells from different locations in the human body. The clustering of these primary cells reveals that most cells in the human body share a few broad transcriptional programs, which define five major cell types: epithelial, endothelial, mesenchymal,...

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Veröffentlicht in:Genome Res
Hauptverfasser: Breschi, Alessandra, Muñoz-Aguirre, Manuel, Wucher, Valentin, Davis, Carrie A., Garrido-Martín, Diego, Djebali, Sarah, Gillis, Jesse, Pervouchine, Dmitri D., Vlasova, Anna, Dobin, Alexander, Zaleski, Chris, Drenkow, Jorg, Danyko, Cassidy, Scavelli, Alexandra, Reverter, Ferran, Snyder, Michael P., Gingeras, Thomas R., Guigó, Roderic
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397875/
https://ncbi.nlm.nih.gov/pubmed/32759341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.263186.120
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