Apolipoprotein E Signals via TLR4 to Induce CXCL5 Secretion by Asthmatic Airway Epithelial Cells

The primary function of APOE (apolipoprotein E) is to mediate the transport of cholesterol- and lipid-containing lipoprotein particles into cells by receptor-mediated endocytosis. APOE also has pro- and antiinflammatory effects, which are both context and concentration dependent. For example, Apoe(−...

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Bibliographic Details
Published in:Am J Respir Cell Mol Biol
Main Authors: Kalchiem-Dekel, Or, Yao, Xianglan, Barochia, Amisha V., Kaler, Maryann, Figueroa, Debbie M., Karkowsky, William B., Gordon, Elizabeth M., Gao, Meixia, Fergusson, Maria M., Qu, Xuan, Liu, Poching, Li, Yuesheng, Seifuddin, Fayaz, Pirooznia, Mehdi, Levine, Stewart J.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2020
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397770/
https://ncbi.nlm.nih.gov/pubmed/32338995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0209OC
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