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Lineage plasticity in cancer: a shared pathway of therapeutic resistance

Lineage plasticity, an ability to transition from one committed developmental pathway to another, has been proposed as a source of intratumoral heterogeneity and tumor adaptation to adverse environments including exposure to targeted anti-cancer treatments. Tumor conversion to a different histologic...

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Библиографические подробности
Опубликовано в: :Nat Rev Clin Oncol
Главные авторы: Quintanal-Villalonga, Álvaro, Chan, Joseph M., Yu, Helena A, Pe’er, Dana, Sawyers, Charles L., Sen, Triparna, Rudin, Charles M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397755/
https://ncbi.nlm.nih.gov/pubmed/32152485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-020-0340-z
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