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Stability of Plasmid and Viral Banks Supporting the cGMP Manufacture of Q-Griffithsin from a TMV-based Viral Vector
The “whole genome” TMV-based expression system, Geneware(®), was used in the cGMP production of the plant-made pharmaceutical Q-Griffithsin and demonstrates stable expression for up to a two-year period. Virion and plasmid banks which contained viral cDNA and a Q-Griffithsin sequence were able to pr...
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| Publicado no: | J Biotechnol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397727/ https://ncbi.nlm.nih.gov/pubmed/32553533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2020.06.009 |
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