Tolerability and efficacy of vortioxetine versus SSRIs in elderly with major depression. Study protocol of the VESPA study: a pragmatic, multicentre, open-label, parallel-group, superiority, randomized trial

INTRODUCTION: Depression is a highly prevalent condition in the elderly, with a vast impact on quality of life, life expectancy, and medical outcomes. Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed agents in this condition and, although generally safe, tolerability...

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Veröffentlicht in:Trials
Hauptverfasser: Ostuzzi, Giovanni, Gastaldon, Chiara, Barbato, Angelo, D’Avanzo, Barbara, Tettamanti, Mauro, Monti, Igor, Aguglia, Andrea, Aguglia, Eugenio, Alessi, Maria Chiara, Amore, Mario, Bartoli, Francesco, Biondi, Massimo, Bortolaso, Paola, Callegari, Camilla, Carrà, Giuseppe, Caruso, Rosangela, Cavallotti, Simone, Crocamo, Cristina, D’Agostino, Armando, De Fazio, Pasquale, Di Natale, Chiara, Giusti, Laura, Grassi, Luigi, Martinotti, Giovanni, Nosé, Michela, Papola, Davide, Purgato, Marianna, Rodolico, Alessandro, Roncone, Rita, Tarsitani, Lorenzo, Turrini, Giulia, Zanini, Elisa, Amaddeo, Francesco, Ruggeri, Mirella, Barbui, Corrado
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Study Protocol
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397635/
https://ncbi.nlm.nih.gov/pubmed/32746941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04460-6
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