Imbalance in T Follicular Helper Cells Producing IL-17 Promotes Pro-inflammatory Responses in MuSK Antibody Positive Myasthenia Gravis

A detailed understanding of the role of Tfh cells in MuSK-antibody positive myasthenia gravis (MuSK-MG) is lacking. We characterized phenotype and function of Tfh cells in MuSK-MG patients and controls. We found similar overall Tfh and follicular regulatory (Tfr) T cell frequencies in MuSK-MG and he...

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Pubblicato in:J Neuroimmunol
Autori principali: Li, Yingkai, Guptill, Jeffrey T., Russo, Melissa A., Howard, James F., Massey, Janice M., Juel, Vern C., Hobson-Webb, Lisa D., Emmett, Doug, Chopra, Manisha, Raja, Shruti, Liu, Weibin, Yi, John S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397478/
https://ncbi.nlm.nih.gov/pubmed/32497931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2020.577279
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