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Histone Deacetylase Inhibition Attenuates Aortic Remodeling in Rats under Pressure Overload

The use of histone deacetylase (HDAC) inhibitor is a novel therapeutic strategy for cardiovascular disease. Studies have shown that many HDAC inhibitors have the ability to reduce the aortic remodeling in various animal models. We hypothesized that the HDAC inhibitor, MGCD0103 (MGCD), attenuates aor...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Jung, Hanna, Lee, Eunjo, Kim, Inkyeom, Kim, Gun Jik
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397417/
https://ncbi.nlm.nih.gov/pubmed/32775424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4705615
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