TCGA Pan-Cancer Genomic Analysis of Alternative Lengthening of Telomeres (ALT) Related Genes

Telomere maintenance mechanisms (TMM) are used by cancer cells to avoid apoptosis, 85–90% reactivate telomerase, while 10–15% use the alternative lengthening of telomeres (ALT). Due to anti-telomerase-based treatments, some tumors switch from a telomerase-dependent mechanism to ALT; in fact, the co-...

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Pubblicato in:Genes (Basel)
Autori principali: Armendáriz-Castillo, Isaac, López-Cortés, Andrés, García-Cárdenas, Jennyfer, Guevara-Ramírez, Patricia, Leone, Paola E., Pérez-Villa, Andy, Yumiceba, Verónica, Zambrano, Ana K., Guerrero, Santiago, Paz-y-Miño, César
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397314/
https://ncbi.nlm.nih.gov/pubmed/32708340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11070834
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