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PTEN Alterations and Their Role in Cancer Management: Are We Making Headway on Precision Medicine?
Alterations in the tumor suppressor phosphatase and tensin homolog (PTEN) occur in a substantial proportion of solid tumors. These events drive tumorigenesis and tumor progression. Given its central role as a downregulator of the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mT...
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| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397204/ https://ncbi.nlm.nih.gov/pubmed/32605290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11070719 |
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