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Synthesis of Polyoxygenated Heterocycles by Diastereoselective Functionalization of a Bio-Based Chiral Aldehyde Exploiting the Passerini Reaction

A chiral bio-based building block, prepared by the lipase-mediated desymmetrization of an erythritol derivative, was further functionalized and then submitted to stereoselective Passerini reactions, allowing the synthesis of a small library of new molecules. Thanks to the presence of different funct...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Vitali Forconesi, Gabriella, Banfi, Luca, Basso, Andrea, Lambruschini, Chiara, Moni, Lisa, Riva, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397154/
https://ncbi.nlm.nih.gov/pubmed/32679733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25143227
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