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High Throughput Virtual Screening to Discover Inhibitors of the Main Protease of the Coronavirus SARS-CoV-2

We use state-of-the-art computer-aided drug design (CADD) techniques to identify prospective inhibitors of the main protease enzyme, 3CL(pro) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19. From our screening of over one million compounds including approved drug...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Olubiyi, Olujide O., Olagunju, Maryam, Keutmann, Monika, Loschwitz, Jennifer, Strodel, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396980/
https://ncbi.nlm.nih.gov/pubmed/32668701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25143193
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