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Rational Design of Antigen Incorporation Into Subunit Vaccine Biomaterials Can Enhance Antigen-Specific Immune Responses

Peptide subunit vaccines increase safety by reducing the risk of off-target responses and improving the specificity of the induced adaptive immune response. The immunogenicity of most soluble peptides, however, is often insufficient to produce robust and lasting immunity. Many biomaterials and deliv...

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Опубликовано в: :Front Immunol
Главные авторы: Tsoras, Alexandra N., Wong, Kong M., Paravastu, Anant K., Champion, Julie A.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396695/
https://ncbi.nlm.nih.gov/pubmed/32849524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01547
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