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Naturally Derived Heme-Oxygenase 1 Inducers and Their Therapeutic Application to Immune-Mediated Diseases

Heme oxygenase (HO) is the primary antioxidant enzyme involved in heme group degradation. A variety of stimuli triggers the expression of the inducible HO-1 isoform, which is modulated by its substrate and cellular stressors. A major anti-inflammatory role has been assigned to the HO-1 activity. The...

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Publicado en:Front Immunol
Main Authors: Funes, Samanta C., Rios, Mariana, Fernández-Fierro, Ayleen, Covián, Camila, Bueno, Susan M., Riedel, Claudia A., Mackern-Oberti, Juan Pablo, Kalergis, Alexis M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396584/
https://ncbi.nlm.nih.gov/pubmed/32849503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01467
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