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TXNIP induces growth arrest and enhances ABT263‐induced apoptosis in mixed‐lineage leukemia‐rearranged acute myeloid leukemia cells

Thioredoxin‐interacting protein (TXNIP) has been widely recognized as a tumor suppressor in various cancers, including liver, breast, and thyroid cancers. Although TXNIP is epigenetically silenced in acute myeloid leukemia (AML) cells, as in many cancer cells, its role in leukemogenesis remains elus...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:FEBS Open Bio
Main Authors: Noura, Mina, Matsuo, Hidemasa, Koyama, Asami, Adachi, Souichi, Masutani, Hiroshi
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396447/
https://ncbi.nlm.nih.gov/pubmed/32511893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12908
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