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Quantitative Measurement of Redox State in Human Brain by (31)P MRS at 7T with Spectral Simplification and Inclusion of Multiple Nucleotide Sugar Components in Data Analysis

PURPOSE: To develop a simplified method for quantitative measurement of NAD(+)/NADH levels in human brain by (31)P MRS without interference from the α-ATP signal and with inclusion of multiple UDP-sugar components. METHODS: Simple pulse-acquire (31)P MR spectra were collected at 7T with and without...

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Bibliografiske detaljer
Udgivet i:Magn Reson Med
Main Authors: Ren, Jimin, Malloy, Craig R., Sherry, A. Dean
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396304/
https://ncbi.nlm.nih.gov/pubmed/32385936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.28306
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