Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype

The human choroidal vasculature is subject to age-related structural and gene expression changes implicated in age-related macular degeneration (AMD). In this study, we performed both bulk and single-cell RNA sequencing on infant (n = 4 for bulk experiments, n = 2 for single-cell experiments) and ad...

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Pubblicato in:Microvasc Res
Autori principali: Voigt, Andrew P, Whitmore, S. Scott, Mulfaul, Kelly, Chirco, Kathleen R, Giacalone, Joseph C, Flamme-Wiese, Miles J, Stockman, Adam, Stone, Edwin M, Tucker, Budd A, Scheetz, Todd E, Mullins, Robert F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396301/
https://ncbi.nlm.nih.gov/pubmed/32531351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2020.104031
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