TEAD4 ensures postimplantation development by promoting trophoblast self-renewal: An implication in early human pregnancy loss

Early pregnancy loss affects ∼15% of all implantation-confirmed human conceptions. However, evolutionarily conserved molecular mechanisms that regulate self-renewal of trophoblast progenitors and their association with early pregnancy loss are poorly understood. Here, we provide evidence that transc...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Saha, Biswarup, Ganguly, Avishek, Home, Pratik, Bhattacharya, Bhaswati, Ray, Soma, Ghosh, Ananya, Rumi, M. A. Karim, Marsh, Courtney, French, Valerie A., Gunewardena, Sumedha, Paul, Soumen
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395512/
https://ncbi.nlm.nih.gov/pubmed/32669432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002449117
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