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Exploiting evolutionary trade-offs for posttreatment management of drug-resistant populations
Antibiotic resistance frequently evolves through fitness trade-offs in which the genetic alterations that confer resistance to a drug can also cause growth defects in resistant cells. Here, through experimental evolution in a microfluidics-based turbidostat, we demonstrate that antibiotic-resistant...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7395499/ https://ncbi.nlm.nih.gov/pubmed/32661175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003132117 |
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