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Transferrin receptor 1-mediated iron uptake plays an essential role in hematopoiesis

Transferrin receptor 1 (Tfr1) mediates the endocytosis of diferric transferrin in order to transport iron, and Tfr1 has been suggested to play an important role in hematopoiesis. To study the role of Tfr1 in hematopoiesis, we generated hematopoietic stem cell (HSC) specific Tfr1 knockout mice. We fo...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Wang, Shufen, He, Xuyan, Wu, Qian, Jiang, Li, Chen, Liyun, Yu, Yingying, Zhang, Pan, Huang, Xin, Wang, Jia, Ju, Zhenyu, Min, Junxia, Wang, Fudi
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395265/
https://ncbi.nlm.nih.gov/pubmed/31601687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.224899
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